Search results for "Transcription Factor AP-2"

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Association between neonatal temperament,SLC6A4,DRD4and a functional polymorphism located inTFAP2B

2011

Genetic studies on human personality have provided little satisfactory results to date mainly because of the complexity of this trait. Neonatal temperament using observational measures is an alternative phenotype to approach genetics to human behavior. An association study was conducted on 117 Caucasian newborns. Their temperament was evaluated using the Neonatal Behavior Assessment Scale 48 h after birth. Thirteen polymorphisms in the SLC6A4, DRD4 and TFAP2B genes were genotyped. Linear regression was performed to analyze data, and Bonferroni correction was applied. To check the functional effect of the TFAP2B Indel Intron 2 polymorphism, reporter gene luciferase assays using a mouse corti…

MaleGenotypemedia_common.quotation_subjectMinisatellite RepeatsBiologyBehavioral NeuroscienceExonGeneticsHumansAlleleTemperamentIndelGeneAllelesGenetic Association Studiesmedia_commonSerotonin Plasma Membrane Transport ProteinsGeneticsPolymorphism GeneticReceptors Dopamine D4Infant NewbornIntronVariable number tandem repeatReal-time polymerase chain reactionTranscription Factor AP-2NeurologyInfant BehaviorFemaleTemperamentGenes, Brain and Behavior
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